FACE-Q ANALYSIS OF BOTULINUM TOXIN APPLICATION IN AESTHETIC MEDICINE

Authors

  • Sabina Radonja Magic Crystal d.o.o., Sarajevo, Bosnia and Herzegovina
  • Fahira Imamović University of Sarajevo - Faculty of Health Studies, Sarajevo, Bosnia and Herzegovina

Keywords:

botulinum toxin, botox, effects, safety

Abstract

The number of aesthetic procedures worldwide, as well as in our country, is growing, and there is a noticeable increase in the number of men as patients of aesthetic medicine. This research analyzes the effects of botulinum toxin application in aesthetic medicine and its safety profile.
Subjects and research methods: The research was conducted from November 1, 2024, to March 10, 2025. This study used the FACE-Q aesthetic module, which was developed for facial aesthetic procedures and proved to be a reliable instrument for measuring patient-reported outcomes after treatment.
Results: The study included 29 (29%) male and 71 (71%) female participants. The results indicate a significant difference between pre- and post-treatment assessments in all domains of the FACE-Q scales, and all findings are statistically highly significant (p < 0.001). The mean value of the appearance satisfaction scale increased from 61.33 ± 18.21 to 89.5 ± 5.73, indicating a strong improvement in subjective perception of appearance. An even more pronounced increase was recorded on the skin appearance satisfaction scale, where the mean value increased from 49.06 ± 18.09 before treatment to 91.64 ± 6.14 after treatment, which represents the largest absolute shift in this analysis. Wrinkle related scales also show a strong change.
Conclusion: The post-treatment results indicate a high degree of satisfaction with all aspects of facial appearance, particularly with a pronounced sense of harmony and aesthetic balance. These findings indicate the success of the treatment in improving subjective face perception and can serve as a strong argument for its efficacy in clinical and aesthetic practice.

References

Ascher, B., Rzany, B., Kestemont, P., Hilton, S., Heckmann, M., Bodokh, I., Noah, EM., Boineau, D., Kerscher M., Volteau, M., Le Berre, P., & Picaut, P. (2020). Significantly Increased Patient Satisfaction Following Liquid Formulation AbobotulinumtoxinA Treatment in Glabellar Lines: FACE-Q Outcomes From a Phase 3 Clinical Trial. Aesthet Surg J. 40(9):1000-1008.

Carruthers, J., Fournier , N., Kerscher, M., Ruiz-Avila, J., Trindade de Almeida, AR., & Kaeuper, G. (2013). The convergence of medicine and neurotoxins: a focus on botulinum toxin type A and its application in aesthetic medicinea global, evidence-based botulinum toxin consensus education initiative: part II: incorporating botulinum toxin into aesthetic clinical practice. Dermatol Surg. 39(3 Pt 2):510-25.

Costa, ACF., Silva, ECD., & Gondim, DV. (2022). Botulinum Toxin in Facial Aesthetics Affects the Emotion Process: A Meta-analysis of Randomized Controlled Trials. Clin Psychopharmacol Neurosci. 20(4):600-608

Dayan, S., Joseph, J., Moradi, A., Lorenc, Z.P., Coleman, K., Ablon, G., Kaufman-Janette, J., Cox, SE., Campbell, A., Munavalli, G., & Prygova I. (2022). Subject satisfaction and psychological well-being with escalating abobotulinumtoxin A injection dose for the treatment of moderate to severe glabellar lines. J Cosmet Dermatol. 21(6):2407-2416.

Etrusco, A., Geru, M., Laganà, AS., Chiantera, V., Giannini, A., & Buzzaccarini, G. (2023). Use of botulinum toxin in aesthetic medicine and gynaecology: current approaches, controversies, and future directions. Prz Menopauzalny. 22(3):155-160.

Fagien, S., & Carruthers, JD. (2008). A comprehensive review of patient-reported satisfaction with botulinum toxin type a for aesthetic procedures. Plast Reconstr Surg.122:1915-1925.

Hankins, CL., Strimling, R., & Rogers, GS. (1998). Botulinum A toxin for glabellar wrinkles. Dose and response Dermatol Surg. 24: 1181-1183.

Huang, W., Rogachefsky, AS., & Foster, JA. (2000). Browlift with botulinum toxin. Dermatol Surg. 26: 55-60.

Lambros, V. (2008). Models of facial aging and implications for treatment. Clin Plast Surg. 35: 319-327.

Morhy, ON., Sisnando, AL., Câmara-Souza, MB., Carbone, AC., & De la Torre Canales, G. (2023). High Levels of Physical Activity Reduce the Esthetic Durability of Botulinum Toxin Type A: A Controlled Single-Blind Clinical Trial. Toxins (Basel). 15(7):46.

Ottenhof, MJ., Veldhuizen, IJ., Hensbergen, LJV., Blankensteijn, LL., Bramer, W., Lei, BV., Hoogbergen, M., Hulst, RRWJ., & Sidey-Gibbons, CJ. (2022). The Use of the FACE-Q Aesthetic: A Narrative Review. Aesthetic Plast Surg. 46(6):2769-2780.

Pereira, IN., & Hassan, H. (2022). Impact of botulinum toxin for facial aesthetics on psychological well-being and quality of life: Evidence-based review. J Plast Reconstr Aesthet Surg. 75(12):4450-4463.

Pribitkin, EA., Greco, TM., Goode, RL., et al. (1997). Patient selection in the treatment of glabellar wrinkles with botulinum toxin type A injection. Arch Otolaryngol Head Neck Surg. 123: 321-326.

Wieder, JM., & Moy, RL. (1998). Understanding botulinum toxin. Surgical anatomy of the frown, forehead, and periocular region. Dermatol Surg. 24: 1172-1174.

Downloads

Published

2025-10-06

How to Cite

Radonja, S., & Imamović, F. (2025). FACE-Q ANALYSIS OF BOTULINUM TOXIN APPLICATION IN AESTHETIC MEDICINE. KNOWLEDGE - International Journal , 72(4), 497–501. Retrieved from http://ojs.ikm.mk/index.php/kij/article/view/7809

Most read articles by the same author(s)