DOES INHALATION SATUREJA MONTANA OIL PRODUCED BRONHODILATATOR RESPONSE IN ASTHMA PATIENTS
Keywords:
Satureja montana oil, asthma, bronchodilatator responceAbstract
Previous research have shown that the tested essential oils of Satureja species had a different chemical composition of pharmacologically active compounds. Apply of Satureja montana oil for bronchospasm in humans is rare. The purpose of this study was to investigate the chemical composition of Satureja montana L oil collected in Montenegro and the possible bronchodilator response in patients with asthma after inhalation of this oil.The chemical analysis of the essential oil, performed by Gas chromatography method. S. montana oil was plentiful in monoterpenes with thymol (54.09%), p-cymene (11.05%), α-pinene (6.1%), carvacol (4.87%) and borneol (2.76%) were present in a high percentage. In total 90 asthma patients divided in three groups. Control groups 1,2 had conventional, physical therapy. Experimental group used to inhale 5% Satureja m.oil at 10 days protocol and conventional therapy. Lung function test was performed in all group. Experimental group had a significant improvement on PEF ( 7.10%), FEV1 ( 9%), FVC ( 7.6%).Conversely, both control groups had relative mean improvement: PEF( 2.7%; 2.8%), FEV1 (3.6%; 4.5%), FVC (4.7%;5.3%).The results indicated that inhalation of Satureja Montana oil provided bronchodilatator responce in asthma patients, and produced better lung function test results than conventional therapy.
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