EFFECTIVENESS OF THE "MICRONEEDLING WITH ELECTROPORATION" METHOD IN AGING SKIN - CASE REPORT
Keywords:
antiaging, microneedles, electroporation, skinAbstract
Skin aging is a natural physiological process in which a number of changes occur in the quality and strength of the skin. In addition, there are a number of exogenous and endogenous factors that accelerate it and contribute to the earlier appearance of the signs of aging - wrinkles, sagging, changes in skin color, etc. Aging skin is the subject of a number of researches and studies examining the processes and causes of the changes that occur. As a result, cosmetic products and aesthetic procedures known as "anti-aging" are developed and created. Their role is to slow down aging processes by affecting the causes and supporting the regenerative abilities of the skin. In recent years, much attention has been paid to the development of procedures for skin regeneration through the application of microinvasive needling. This report aims to track the effectiveness of the Microneedling with Electroporation method in the care of aging skin. A case of a client with aging skin is presented, where 2 procedures were performed on the face and neck area. For the purposes of the report, skin analysis methods were used, which included the following clinical scales - Global Aesthetic Improvement Scale (GAIS), the Wrinkle Assessment Scale (WAS), photographic images. The evaluation of the effectiveness of the method is based on the changes on the skin surface observed in the individual stages – before the first procedure, between the first and second procedures and after the second procedure. The analysis of the obtained results shows a change in the studied skin parameters, with degrees of improvement recorded in each of them - relief; wrinkles (number, depth and width); color, turgor, etc. The use of microneedle electroporation in the care of aging skin is a reliable approach, with a good degree of effectiveness and gentle achievement of results.
References
Alrabiah A.l, M. Alduailij, M. Crane (2019) “Computer-based Approach to Detect Wrinkles and Suggest Facial Fillers” International Journal of Advanced Computer Science and Applications(IJACSA), 10(9),. http://dx.doi.org/10.14569/IJACSA.2019.0100941
Aust, M., S. Bahte, D. Fernandes (2013). Illustrated Guide to Percutaneous Collagen Induction, 1st Edition 2013, Quintessence Publishing Company, Inc, KVM Verlag USE, ISBN 978-1-85097-253-2
Carruthers A., Carruthers J. A (2010) Validated facial grading scale: the future of facial ageing measurement tools? J Cosmet Laser Ther. Oct;12(5):235-41. doi: 10.3109/14764172.2010.514920. PMID: 20825260.
Chang, Ts., M. Tsai (2022). "Classifying Conditions of Speckle and Wrinkle on the Human Face: A Deep Learning Approach" Electronics 11, no. 21: 3623. https://doi.org/10.3390/electronics11213623
DiBernardo, G., B. DiBernardo (2018). Prediction of Treatment Outcomes for Neck Rejuvenation Utilizing a Unique Classification System of Treatment Approach Using a 1440-nm Side-Firing Laser. Aesthet Surg J. May 15;38(suppl_2):S43-S51. doi: 10.1093/asj/sjy066. PMID: 29767718.
Gold, M., J. Biron, A. Wilson (2020). Improvement of skin texture and wrinkles using radiofrequency ultra-thin electrode technology. J Cosmet Dermatol. Feb;19(2):388-392. doi: 10.1111/jocd.13239. Epub 2019 Dec 12. PMID: 31829510.
Hong, J., T. Kwon, J. Kim, B. Lee, B. Kim (2020). Prospective, preclinical comparison of the performance between radiofrequency microneedling and microneedling alone in reversing photoaged skin. J Cosmet Dermatol. May;19(5):1105-1109. doi: 10.1111/jocd.13116. Epub 2019 Sep 6. PMID: 31490628.
Jain R, Huang P, Ferraz RM. (2017) A new tool to improve delivery of patient-engaged care and satisfaction in facial treatments: the Aesthetic Global Ranking Scale. J Cosmet Dermatol. Mar;16(1):132-143. doi: 10.1111/jocd.12297. Epub 2016 Dec 16. PMID: 27987257.
Lemperle, G. (2015). A Classification of Facial Wrinkles. UC San Diego. Retrieved from https://escholarship.org/uc/item/5367f9z0
Nava-Arzaluz, M., I. Calderon-Lojero, D. Quintanar-Guerrero, R. Villalobos-Garcia, A. Ganem-Quintanar (2012) Microneedles as transdermal delivery systems: combination with other enhancing strategies. Curr Drug Deliv. Jan;9(1):57-73. doi: 10.2174/156720112798376078. PMID: 21864254.
Sasaki, G. (2017) Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns. Aesthet Surg J. Jan;37(1):71-83. doi: 10.1093/asj/sjw120. Epub 2016 Aug 16. PMID: 27530764.
Savoia, A., C. Accardo, F. Vannini, et al. (2014). Outcomes in Thread Lift for Facial Rejuvenation: a Study Performed with Happy Lift™ Revitalizing. Dermatol Ther (Heidelb) 4, 103–114 https://doi.org/10.1007/s13555-014-0041-6
Tan, M., C. Jo, A. Chapas, S. Khetarpal, J. Dover (2021) Radiofrequency Microneedling: A Comprehensive and Critical Review. Dermatol Surg. Jun 1;47(6):755-761. doi: 10.1097/DSS.0000000000002972. PMID: 33577211.
Yan, K., H. Todo, K. Sugibayashi (2010) Transdermal drug delivery by in-skin electroporation using a microneedle array. Int J Pharm. Sep 15;397(1-2):77-83. doi: 10.1016/j.ijpharm.2010.06.052. Epub 2010 Jul 7. PMID: 20619329.
