ACCOMPANYING THE DISEASE OR SYNDROME OF NERVOUS-REGULATORY DYSFUNCTION?

Abstract

Introduction: In medical practice, concomitant diseases are important for the healing process and how directly they are related to the genesis of the active disease, as well as the likelihood of being subject to uniform regulatory mechanisms. This study presents concomitant diseases in which cancer develops. Aim and methodology: The article aims to present a constellation of diseases in which the oncological gynecological disease has developed. Statistics processed with Excel were used. Results: The study covers one hundred and ninety-six clinical cases of patients with gynecological malignancies who are candidates for surgical treatment. The health status was studied with an emphasis on the presence of concomitant diseases. Thirty-nine cases were not diagnosed with concomitant diseases. In the remaining one hundred and thirty cases there is a recurrence of concomitant diseases - hypertension, diabetes and Hashimoto's thyroiditis and one case of hyperthyroidism. Forty percent of cases were diagnosed with concomitant hypertension. Eighteen percent of cases have diabetes mellitus as a concomitant disease. Fourteen percent of cases were diagnosed with concomitant hypertension and non-insulin-dependent diabetes mellitus as a concomitant disease. In eight percent of cases, the presence of autoimmune thyroiditis - Hashimoto's syndrome as a concomitant disease. Discussion: The common aspect between the three diseases: hypertension, diabetes and Hashimoto's autoimmune thyroiditis, is that they are in violation of metabolism, therefore with a violation of homeostasis of the human body.
Every disease is a condition of the body that is caused by the influence of strong stimuli, which disturbs the balance of the internal environment, namely homeostasis. Blood pressure, along with temperature, and blood composition: water, sodium, calcium, acidity and alkalinity, glucose are the most important factors in homeostasis. The mechanism of regulation is the negative feedback, which aims to slow down or stop the processes, which automatically maintains the balance. Conclusion: The participation of the same organs in the regulation of endocrine diseases - pituitary, hypothalamus, the role of the sympathetic nervous system and impaired homeostasis, may explain the unity in the constellation of oncological gynecological disease - arterial hypertension, autoimmune diabetes mellitus, noninsulinemia. Probably it is a question of disturbed homeostasis in a percentage of cases of oncological disease with concomitant diseases, forming a syndrome of neuro-regulatory dysfunction.