RELATIONSHIP BETWEEN ABO BLOOD GROUP AND OBESITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Authors

  • Julie Lubica Rizova Faculty of Medical Sciences, Goce Delcev University, Stip, Republic of North Macedonia
  • Gordana Kamceva Mihailova Faculty of Medical Sciences, Goce Delcev University, Stip, Republic of North Macedonia

Keywords:

ABO blood type, obesity, BMI, type 2 diabetes mellitus

Abstract

Differences in blood, resulting from the presence or absence of antigens that correspond to specific blood types, have indirect implications for disease susceptibility. Research has shown that people with blood type AB or A may have an increased risk of developing type 2 diabetes compared to those with blood type O. Medical News Today reported that women with blood type AB+ had a 26% higher risk of developing type 2 diabetes. Other research suggests that individuals with blood type B may be more susceptible to obesity compared to those with blood type O or A. One study found that blood type AB has a lower risk of developing obesity compared to other blood types. Obesity is a major risk factor for developing type 2 diabetes, as excess body weight can lead to insulin resistance.
Aim: Our aim of the paper is to show which blood type is most prevalent in obese patients with type 2 diabetes mellitus and whether this is statistically significant.
Materials and Methods: The data for this scientific paper were collected during blood donation campaigns that were currently being carried out during 2025. For each participant, the following data were recorded: ABO blood group, body mass index (BMI), age and gender. All data are presented in tables and graphs.
Results: A total of 197 blood donors were included in this study. Of the total number of blood donors 197, 62 (31.5%) patients were diagnosed with diabetes mellitus and received tablet therapy. Male gender was more common. A positive blood group was the most common blood group in patients, but the most common blood group was B- in patients with proven diabetes mellitus type 2. Of the total number of patients with DM type 2, obesity was most prevalent in those with AB- blood group.
Conclusion: The relationship between blood type, obesity, and diabetes is complex and may involve genetic, lifestyle, and environmental factors. Larger and more detailed studies are needed to fully understand the interaction between these factors and the possible biological mechanisms. These findings may have clinical relevance in identifying subgroups of patients at increased risk and in a personalized approach to the management of type 2 diabetes mellitus.

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Published

2025-12-14

How to Cite

Lubica Rizova, J., & Kamceva Mihailova, G. (2025). RELATIONSHIP BETWEEN ABO BLOOD GROUP AND OBESITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. KNOWLEDGE - International Journal , 73(4), 691–694. Retrieved from https://ojs.ikm.mk/index.php/kij/article/view/7956

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